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Oesophageal Squamous Cell Carcinoma African Prevention Research (ESCCAPE) is a collaborative research effort to investigate the etiological epidemiology of squamous cell carcinoma in Africa. This cancer ranks amongst the three most common cancers in several countries in East Africa and in the eastern parts of South Africa, but intriguingly it is extremely rare in West Africa. Its prognosis is poor; thus, if modifiable factors are responsible for the disproportionately high incidence rates of this cancer in East Africa, identifying them may inform primary prevention efforts.

ESCCAPE has received funding from IARC, from the United States National Cancer Institute to support Eldoret in western Kenya, and from the Union for International Cancer Control (UICC) to support Dr Oresto Munishi in the United Republic of Tanzania.